Mechanical Design and Analysis of a Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates
نویسندگان
چکیده
منابع مشابه
A contusion model of severe spinal cord injury in rats.
The translational potential of novel treatments should be investigated in severe spinal cord injury (SCI) contusion models. A detailed methodology is described to obtain a consistent model of severe SCI. Use of a stereotactic frame and computer controlled impactor allows for creation of reproducible injury. Hypothermia and urinary tract infection pose significant challenges in the post-operativ...
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During traumatic spinal cord injury (SCI), the spinal cord is subject to external displacements that result in damage of neural tissues. These displacements produce complex internal deformations, or strains, of the spinal cord parenchyma. The aim of this study is to determine a relationship between these internal strains during SCI and primary damage to spinal cord gray matter (GM) in an in viv...
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Background: The spinal cord trauma is a lost physical performance that causes physical limitations in addition to mental, social and economic disadvantages. The mouth and tooth health is known as one of the related issues to the physical quality of life. Providing the conditions of the more independence for these people in brushing teeth can improve the level of mouth and tooth hygiene. The aim...
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Background: Chondroitinase ABC (cABC), due to its loosening impact on the extracellular matrix scaffold, has been used to enhance regeneration of injured axonal tracts after spinal cord injury (SCI). However, cABC thermal instability at physiological temperature has limited its clinical application. The disaccharide trehalose has been shown to increase the stability of cABC in body temperature....
متن کاملChanges in Urinary Bladder Structure and Systemic Inflammation Response Following Incomplete Transection versus Contusion Spinal Cord Injury in Rat Model
Objective- The current study was conducted to evaluate changes in the urinary bladder structure and leukocyte profile as an important index of the systemic inflammation response for two different types of spinal cord injury (SCI) in a rat model. Design- Experimental Study.Animals- Forty adult healthy female Sprague-Dawley rats.<br /...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2016
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2015.3974